With the flood of ice water challenge videos saturating the internet, I thought I'd draw attention to a possible supplement to ALS / Lou Gehrig's Disease treatment. If you can, please make a donation to the ALS association. My goal with this article is to provide as much reference material possible for any arguments or essays that you may be concocting about cannabis - or simply for educational purposes.
- Marijuana in the management of amyotrophic lateral sclerosis (abst - 2001)
- Survey of cannabis use in patients with amyotrophic lateral sclerosis. (abst - 2004)
- Delayed disease progression in ALS mice by treatment with a cannabinoid. (abst - 2004)
- Cannabis' Potential Exciting Researchers in Treatment of ALS, Parkinson's Disease -URB597 (news - 2004 )
- Cannabis Relieves Lou Gehrigs Symptoms - New Study (news - 2004)
- Marijuana-like compounds may aid array of debiliating conditions ranging from Parkinson's to pain (news – 2004)
- Cannabinol delays symptom onset in SOD1 (G93A transgenic mice without affecting survival. (abst - 2005))
- Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice (full - 2006)
- AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis. (abst - 2006)
- The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset (full - 2007)
- The endocannabinoid system in targeting inflammatory neurodegenerative diseases (full - 2007)
- Cannabinoids and neuroprotection in motor-related disorders. (abst - 2007)
- The (EndoCannabinoid System in Multiple Sclerosis and Amyotrophic Lateral Sclerosis (abst – 2007))
- The endocannabinoid system in amyotrophic lateral sclerosis. (abst – 2008)
- Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity. (abst - 2008)
- Role of CB2 receptors in neuroprotective effects of cannabinoids. (abst - 2008)
- Emerging Role of the CB2 Cannabinoid Receptor in Immune Regulation and Therapeutic Prospects (full - 2009)
- Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease (full - 2009)
- Cannabinoids and neurodegenerative diseases. (abst - 2009)
- Medical Marijuana and Amyotrophic Lateral Sclerosis (ALS (news – 2009))
- Medical Marijuana and Lou Gehrig's Disease (news – 2009)
- Cannabis and Amyotrophic Lateral Sclerosis: Hypothetical and Practical Applications, and a Call for Clinical Trials. (abst - 2010)
- The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis. (abst - 2010)
- Abnormal sensitivity of cannabinoid CB1 receptors in the striatum of mice with experimental amyotrophic lateral sclerosis. (abst – 2010)
- The endocannabinoid system in gp120-mediated insults and HIV-associated dementia. (abst – 2010)
- Tetrahydrocannabinol (THC for cramps in amyotrophic lateral sclerosis: a randomised, double-blind crossover trial. (abst – 2010))
- Marijuana May Extend Life Expectancy Of Lou Gehrig's Disease Patients, Study Says (news - 2010)
- Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011)
- Cannabinoid receptor signalling in neurodegenerative diseases: a potential role for membrane fluidity disturbance. (full – 2011)
- Single-dose Pharmacokinetics and Tolerability of Oral Delta-9-Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis. (abst – 2012)
- Medical Cannabis Helps ALS Patient Outlive her Own Doctors (news/anecdotal – 2012)
- Interplay of cannabinoid 2 (CB2 receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration (abst – 2013))
- Therapeutic Potential of Cannabinoids in Neurodegenerative Disorders: A Selective Review. (abst – 2013)
- Amyotrophic Lateral Sclerosis Treatment with Ultramicronized Palmitoylethanolamide: A Case Report (abst – 2013)
- Patient pitches medical marijuana at Fla. Capitol (news/anecdotal – 2013)
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