I know how difficult it can be to support your argument for the legalization of cannabis or medical marijuana. It's easy to say that cannabis cures cancer, but where is the evidence behind it? My goal with this article is to provide as much reference material possible for any arguments or essays that you may be concocting about cannabis - or simply for educational purposes. Click the following links to find the appropriate cannabinoids: CBC - CBD - CBDA - CBV - CBG - CBN
CBC / CANNABICHROMENE- Cannabis (hemp positive skin tests and respiratory symptoms (abst - 2000))
- Allergic rhinoconjunctivitis caused by Cannabis sativa pollen (3rd article (full - 2007))
- Cannabaceae Pollen in the Atmosphere of Brianza, Northen Italy. (abst – 2007)
- Sensitization and Allergy to Cannabis sativa Leaves in a Population of Tomato Sensitized Patients. (abst - 2008 )
- Allergic hypersensitivity to cannabis in patients with allergy and illicit drug users. (full – 2011 )
- IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel. (abst – 2011 )
- Molecular allergology in practice: an unusual case of LTP allergy. (abst – 2011)
- Hypersensitivity reactions to marijuana (article – 2012)
- World Allergy Organization Study on Aerobiology for Creating First Pollen and Mold Calendar With Clinical Significance in Islamabad, Pakistan;: A Project of World Allergy Organization and Pakistan Allergy, Asthma & Clinical Immunology Centre of Islamabad. (abst – 2012 )
- Variations and origin of the atmospheric pollen of Cannabis detected in the province of Tetouan (NW Morocco: 2008-2010 (abst – 2012))
- New Food Allergies in a European Non-Mediterranean Region: Is Cannabis sativa to Blame? (abst – 2013 )
- Characterization of Cannabis sativa allergens. (abst – 2013)
CBD/ CANNABIDIOLAntagonist of CB1 and CB2, GPR – 55 and 18 receptors Cannabidiol (CBD) is the second most common compound found in the cannabis plant. It produces a sedative high in contrast to the psychedelic high from THC, making you sleepy at higher doses. It also mitigates the effects of THC (particularly high dose, anxiety filled highs), not by reducing the amount of THC in the bloodstream, but by working it's sedative effects synergistically. The health benefits to CBD seem endless. CBD has been shown to have anti-inflammatory properties, even preventing the body from producing the chemical that causes inflammation. CBD has also been shown to reduce epileptic episodes, resulting in less seizures. CBD has even been found to bind to receptors in cancer cells and induce death. CBD exerts a protective property to damaged neurons, inhibiting the process in which nerves are damaged. Great for injury, protects brain from damage. CBD also fights MRSA, which is resistant to a number of antibiotics. Cannbidiol (CBD) is produced if there is enough CBDA synthase to catalyze Cannabigerolic Acid (CBGA) molecules into rings of Cannabidiolic Acid (CBDA). The CBDA is then converted to CBD through decarboxylation, either through heat or over time. - Phytocannabinoids (news – undated)
- ACCESSING 0.5 to 2.0 GRAMS CBD FRACTIONATING THE PHYTOCANNABINOIDS BY THEIR VAPORIZATION POINTS (article - undated)
- Effects of cannabidiol derivatives on intestinal motility (abst - undated)
- Cannabinoids might reduce spasticity in multiple sclerosis (full - 2000)
- The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis (full - 2000)
- Advantages of polypharmaceutical herbal cannabis compared to single ingredient, synthetic tetrahydrocannabinol (full - 2000)
- Variations of D9-THC content in single plants of hemp varieties (full - 2000)
- Neuroprotective Antioxidants from Marijuana (abst – 2000)
- Different effects of nabilone and cannabidiol on binocular depth inversion in Man. (abst – 2000)
- Synthesis of a primary metabolite of cannabidiol. (abst – 2000)
- Cannabinoids in clinical practice. (abst - 2000)
- Marijuana Extract Helps Arthritis Pain (news - 2000)
- Cannabinoid effects on anxiety-related behaviours and hypothalamic neurotransmitters. (abst - 2001)
- Composition of the essential oils and extracts of two populations of Cannabis sativa L. ssp. spontanea from Austria (forum post/full - 2003)
- Cannabis and the brain. (full - 2003)
- Neuroprotective Effect of(−Δ9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-d-Aspartate-Induced Retinal Neurotoxicity - Involvement of Peroxynitrite (full - 2003))
- Post-ischemic Treatment with Cannabidiol Prevents Electroencephalographic Flattening,Hyperlocomotion and Neuronal Injury in Gerbils. (abst – 2003 )
- Therapeutic potential of cannabinoids in CNS disease. (abst - 2003)
- Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells. (abst - 2003)
- Cannabidiol-transdermal delivery and anti-inflammatory effect in a murine model. (abst - 2003)
- Anti-tumor effects of cannabidiol, a non-psychotropic cannabinoid, on human glioma cell lines (abst - 2003)
- Initial experiences with medicinal extracts of cannabis for chronic pain: Results from 34 ‘N of 1’ studies (full - 2004)
- Neuroprotective effect of cannabidiol, a non-psychoactive component from Cannabis sativa, on β-amyloid-induced toxicity in PC12 cells (full - 2004)
- Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism. (abst – 2004)
- Cannabidiol Preserves Retinal Neurons and Reduces Vascular Permeability in Experimental Diabetes (abst - 2004)
- Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and earlymorning behavior in young adults. (abst - 2004)
- Marijuana-like compounds may aid array of debiliating conditions ranging from Parkinson's to pain (news – 2004)
- Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity (full - 2005)
- Cannabidiol inhibits human glioma cell migration through a cannabinoid receptorindependent mechanism (full - 2005)
- Cannabidiol Prevents Cerebral Infarction Via a Serotonergic 5-Hydroxytryptamine1AReceptor–Dependent Mechanism (full - 2005)
- Cannabidiol lowers incidence of diabetes in non-obese diabetic mice (full - 2005)
- Cannabinol delays symptom onset in SOD1 (G93A transgenic mice without affecting survival. (abst - 2005))
- Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1 and unidentified receptors. (abst – 2005))
- Cannabidiol as an antipsychotic. A double-blind, controlled clinical trial on cannabidiol vs. amisulpride in acute schizophrenia. (abst - 2005)
- Treatment with CBD in oily solution of drug-resistant paediatric epilepsies. (abst - 2005)
- Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. (abst - 2005)
- Pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol. (abst – 2005)
- Chemicals in Cannabis may help mentally ill (news - 2005)
- Neuroprotective and Blood-Retinal Barrier-Preserving Effects of Cannabidiol in Experimental Diabetes (full - 2006)
- Role of the Cannabinoid System in Pain Control and Therapeutic Implications for the Management of Acute and Chronic Pain Episodes (full - 2006)
- A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol. (full - 2006)
- Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug (full - 2006)
- Cannabidiol-Induced Apoptosis in Human Leukemia Cells: A Novel Role of Cannabidiol in the Regulation of p22phox and Nox4 Expression (full - 2006)
- Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma (full - 2006)
- The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. (abst - 2006)
- Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. (abst - 2006)
- Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. (abst – 2006)
- Differential effects of cannabis extracts and pure plant cannabinoids on hippocampal neurones and glia. (abst - 2006)
- The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. (abst - 2006)
- The marijuana component cannabidiol inhibits beta-amyloid-induced tau protein hyperphosphorylation through Wnt/beta-catenin pathway rescue in PC12 cells. (abst - 2006)
- Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NFkappaB involvement. (abst – 2006)
- Cannabidiol inhibits tumour growth in leukaemia and breast cancer (news - 2006)
- Compound found in marijuana may defend against diabetic retinopathy (news – 2006)
- Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. (full - 2007)
- The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9- tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin (full - 2007)
- Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption (full - 2007)
- Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression (full - 2007)
- Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury (full - 2007)
- Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro (full - 2007)
- Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism. (full - 2007)
- Nonpsychoactive Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity (full - 2007)
- Cannabidiol, unlike synthetic cannabinoids, triggers activation of RBL-2H3 mast cells (full – 2007)
- The multidrug transporter ABCG2 (BCRP is inhibited by plant-derived cannabinoids. (full – 2007))
- US Patent Application 20070099987 - Treating or preventing diabetes with cannabidiol (full – 2007)
- Repeated Treatment with Cannabidiol but Not Delta9-tetrahydrocannabinol Has a Neuroprotective Effect Without the Development of Tolerance (abst - 2007)
- Interactions of cannabidiol with endocannabinoid signalling in hippocampal tissue. (abst – 2007)
- Cannabidiol--recent advances. (abst - 2007)
- Who's Afraid of Cannabidiol? (news - 2007)
- Cannabidiol May be Effective in Preventing Bovine Spongiforme Enzephalopathy (Mad Cow Disease (news - 2007))
- Marijuana Compound Shows Promise In Fighting Breast Cancer (news - 2007)
- Cannabis compound cannabidiol CBD 'halts cancer (news - 2007)
- Cannabis compound stops spread of breast cancer: researchers (news - 2007)
- Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Δ9-tetrahydrocannabinol (full - 2008)
- Mediation of Cannabidiol anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor (full - 2008)
- Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)
- Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice (full - 2008)
- Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. (full - 2008)
- Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis (full - 2008)
- Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. (full - 2008)
- US Patent Application 20080262099 - Inhibition of Tumour Cell Migration (full – 2008)
- The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses. (abst - 2008)
- A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cell (abst - 2008)
- 5-Lipoxygenase and anandamide hydrolase (FAAH mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. (abst – 2008))
- The nonpsychoactive cannabis constituent cannabidiol is a wake-inducing agent. (abst - 2008)
- Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders. (abst - 2008)
- Inhibition of Breast Cancer Aggressiveness by Cannabidiol (abst - 2008)
- Scheduling process at DEA - the example of cannabidiol (abst – 2008)
- Therapeutic time window of cannabidiol treatment on delayed ischemic damage via highmobility group box1-inhibiting mechanism. (full – 2009)
- Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells (full – 2009)
- Non-psychotropic plant cannabinoids:new therapeutic opportunities from an ancient herb (full - 2009)
- Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation (full - 2009)
- Evaluation of Prevalent Phytocannabinoids in the Acetic Acid Model of Visceral Nociception (full – 2009)
- The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo (full – 2009)
- Cannabinoids as novel anti-inflammatory drugs. (full - 2009)
- Cannabidiol, a Nonpsychotropic Component of Cannabis, Inhibits Cue-Induced Heroin Seeking and Normalizes Discrete Mesolimbic Neuronal Disturbances (full - 2009)
- Cannabidiol As a Putative Novel Therapy for Diabetic Retinopathy: A Postulated Mechanism of Action as an Entry Point for Biomarker-Guided Clinical Development. (full - 2009)
- Cannabidiol: a promising drug for neurodegenerative disorders? (full - 2009)
- Cannabidiol Attenuates Cisplatin-Induced Nephrotoxicity by Decreasing Oxidative/Nitrosative Stress, Inflammation, and Cell Death (full – 2009)
- The nonpsychotropic cannabinoid cannabidiol modulates and directly activates alpha-1 and alpha-1-Beta glycine receptor function (full – 2009)
- Cannabidiol-induced lymphopenia does not involve NKT and NK cells. (full – 2009)
- Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania (abst – 2009)
- Cannabidiol Attenuates Myocardial Dysfunction, Fibrosis, Inflammation, Cell Death and Interrelated Signaling Pathways Associated With Diabetic Cardiomyopathy (abst - 2009)
- Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and proinflammatory cytokines during experimental periodontitis in rats. (abst - 2009)
- Cannabidiol-2',6'-Dimethyl Ether, a Cannabidiol Derivative, Is a Highly Potent and Selective 15-Lipoxygenase Inhibitor. (abst - 2009)
- Time-dependent vascular actions of cannabidiol in the rat aorta. (abst – 2009)
- Beneficial effects of a Cannabis sativa extract treatment on diabetes-induced neuropathy and oxidative stress. (abst - 2009/a>)
- Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels. (abst – 2009)
- Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis. (abst - 2009)
- Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation. (abst - 2009)
- Cannabidiol for the treatment of psychosis in Parkinson’s disease (abst - 2009)
- Modulation of effective connectivity during emotional processing by Delta9-tetrahydrocannabinol and cannabidiol. (abst - 2009)
- Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9-tetrahydrocannabinol in rats. (abst – 2009))
- Opposite Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology. (abst - 2009)
- Cannabis compound can help cells (news – 2009)
- Cannabis plant extracts could potentially form the basic ingredients for a market-leading diabetes drug (news – 2009)
- Marijuana Chemicals Ease MS Symptoms, Review Confirms (news - 2009)
- Cannabis by product helps reduce effects of Parkinson disease medication (news - 2009)
- International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2 (full – 2010)
- Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors (full – 2010)
- Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain (full - 2010)
- Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis (full - 2010)
- Therapeutical use of the cannabinoids in psychiatry (full – 2010)
- Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. (full - 2010)
- Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo (full - 2010)
- Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardia carrhythmias and reduces infarct size when given at reperfusion. (full – 2010)
- Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (full - 2010)
- Antitumorigenic Effects of Cannabinoids beyond Apoptosis (full - 2010)
- Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy (full - 2010)
- Antidepressant-like effect of Delta(9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full - 2010))
- Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation. (full – 2010)
- Anti-tumoural effects of cannabinoid combinations - Patent TW201002315 (A ― 2010-01-16 (full – 2010))
- Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation.(full– 2010)
- Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis (full - 2010)
- Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke (link to PDF – 2010)
- A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice. (abst – 2010)
- Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. (abst – 2010)
- Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010)
- Decrease of plasminogen activator inhibitor-1 may contribute to the anti-invasive action of cannabidiol on human lung cancer cells. (abst - 2010)
- Regulation of nausea and vomiting by cannabinoids (abst - 2010)
- Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. (abst - 2010)
- Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoformselective and potent inhibitors of human CYP1 enzymes. (abst – 2010)
- Cannabidiol bioavailability after nasal and transdermal application: effect of permeation enhancers. (abst - 2010)
- Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study. (abst - 2010)
- Cannabidiol inhibits cancer cell invasion via upregulation of tissue inhibitor of matrix metalloproteinases-1. (abst - 2010)
- Cannabidiol Enhances the Inhibitory Effects of Δ9-Tetrahydrocannabinol on Human Glioblastoma Cell Proliferation and Survival (abst - 2010)
- Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. (abst - 2010)
- Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania. (abst - 2010)
- Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology (abst - 2010)
- Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. (abst - 2010)
- Cannabidiol attenuates delayed-type hypersensitivity reactions via suppressing T-cell and macrophage reactivity. (abst - 2010)
- Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain. (abst - 2010)
- Disposition of Cannabichromene, Cannabidiol, and Δ9-Tetrahydrocannabinol and its Metabolites in Mouse Brain following Marijuana Inhalation Determined by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (abst - 2010)
- Treatment with cannabidiol reverses oxidative stress parameters, cognitive impairment and mortality in rats submitted to sepsis by cecal ligation and puncture. (abst - 2010)
- Anticonvulsant effects of GWP42006 in vitro and in vivo in rat (abst - 2010)
- The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxicischemic brain damage in mice is mediated by CB(2 and adenosine receptors. (abst – 2010))
- Neural basis of anxiolytic effects of cannabidiol (CBD in generalized social anxiety disorder: a preliminary report (abst - 2010))
- Non-psychoactive cannabis to be unveiled at Annual National Clinical Conference on Cannabis Therapeutics (news - 2010)
- Prescription Marijuana Without "Intoxicating" Effect in Research Stage (news - 2010)
- Key ingredient staves off marijuana memory loss (news - 2010)
- Science: Cannabidiol enhances the anti-cancer effects of THC on human brain cancer cells (news – 2010)
- Pot Compound Mitigates Diabetic Cardiomyopathy (news - 2010)
- Cannabinoids inhibit and may prevent neuropathic pain in diabetes. (news - 2010)
- Lab Notes: Pot Has Benefits for Diabetic Hearts (news - 2010)
- Cannabidiol (CBD as an Anti-Arrhythmic – the Role of the CB1 Receptors (news – 2010))
- The potential for clinical use of cannabinoids in treatment of cardiovascular diseases. (full – 2011)
- Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion (full – 2011)
- Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: an intravital microscopy study (full – 2011)
- Cannabidiol Reduces Aβ-Induced Neuroinflammation and Promotes Hippocampal Neurogenesis through PPARγ Involvement (full – 2011)
- Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimers' disease (full – 2011)
- Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full – 2011)
- Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol (full – 2011)
- Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. (full – 2011)
- Cannabidiol, a Major Phytocannabinoid, as a Potent Atypical Inhibitor for Cytochrome P450 2D6. (full – 2011)
- Brief Report: Cannabidiol Prevents the Development of Cold and Mechanical Allodynia in Paclitaxel-Treated Female C57Bl6 Mice. (full – 2011)
- Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full – 2011)
- Prospects for cannabinoid therapies in basal ganglia disorders. (full – 2011)
- US Patent Application 20110257256 - CANNABINOIDS FOR USE IN TREATING OR PREVENTING COGNITIVE IMPAIRMENT AND DEMENTIA (full - 2011)
- Influence of agroclimatic conditions on content of main cannabinoids in industrial hemp (Cannabis sativa L. (full– 2011))
- Modulation of Auditory and Visual Processing by Delta-9-Tetrahydrocannabinol and Cannabidiol: an fMRI Study. (full – 2011)
- Cannabidiol induces programmed cell death in breast cancer cells by coordinating the crosstalk between apoptosis and autophagy. (full – 2011)
- Phytocannabinoids for use in the treatment of cancer - Patent GB2478595 (A ― 2011-09-14 (full – 2011))
- Identification of cytochrome P450 enzymes responsible for metabolism of cannabidiol by human liver microsomes. (abst – 2011)
- Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent. (abst - 2011)
- Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors. (abst – 2011)
- Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. (abst – 2011)
- The Non-Psychoactive Plant Cannabinoid, Cannabidiol Affects Cholesterol Metabolism-Related Genes in Microglial Cells. (abst – 2011)
- Cannabidiol decreases body weight gain in rats: Involvement of CB2 receptors. (abst - 2011)
- Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in mice. (abst – 2011)
- Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (abst – 2011)
- CANNABIDIOL INHIBITS PATHOGENIC T-CELLS, DECREASES SPINAL MICROGLIAL ACTIVATION AND AMELIORATES MULTIPLE SCLEROSIS-LIKE DISEASE IN C57BL/6 MICE. (abst – 2011)
- Anti-Aversive Effects of Cannabidiol on Innate Fear-Induced Behaviors Evoked by anEthological Model of Panic Attacks Based on a Prey vs the Wild Snake Epicratescenchria crassus Confrontation Paradigm. (abst - 2011)
- Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst – 2011))
- Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus. (abst – 2011))
- A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst – 2011)
- Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. (abst – 2011)
- Cannabidiol potentiates Δ(9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. (abst - 2011))
- Inhibitory Effect of Standardized Cannabis sativa Extract and Its Ingredient Cannabidiol on Rat and Human Bladder Contractility. (abst – 2011)
- Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naïve social phobia patients. (abst – 2011)
- Effects on sleep and dopamine levels of microdialysis perfusion of cannabidiol into the lateral hypothalamus of rats. (abst – 2011)
- Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. (abst – 2011)
- Effect of cannabidiol on sleep disruption induced by the repeated combination tests consisting of open field and elevated plus-maze in rats. (abst – 2011)
- Cannabidiol, a Non-Psychotropic Component of Cannabis, Attenuates Vomiting and Nausea-like Behaviour via Indirect Agonism of 5-HT(1A Somatodendritic: Autoreceptors in the Dorsal Raphe Nucleus. (abst – 2011))
- Regulation of nausea and vomiting by cannabinoids. (abst – 2011)
- The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst – 2011)
- Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. (abst – 2011)
- Cannabidiol Dampens Streptozotocin-Induced Retinal Inflammation by Targeting of Microglial Activation (abst - 2011)
- Plasma and brain pharmacokinetic profile of cannabidiol (CBD, cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour. (abst – 2011))
- Cannabis with high cannabidiol content is associated with fewer psychotic experiences.(abst – 2011)
- A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (abst – 2011)
- Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. (abst – 2011)
- Neural basis of anxiolytic effects of cannabidiol (CBD in generalized social anxiety disorder: a preliminary report. (abst – 2011))
- Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects. (abst – 2011)
- The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives. (abst – 2011)
- Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and cell death (abst – 2011)
- Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death. (abst – 2011)
- Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats. (abst – 2011)
- Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. (abst – 2011)
- Cannabidiol reduces brain damage and improves functional recovery after acute hypoxiaischemia in newborn pigs. (abst – 2011)
- Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury. (abst – 2011)
- Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9 -tetrahydrocannabinol in BV-2 microglial cells (abst – 2011))
- THC and CBD oromucosal spray (Sativex® in the management of spasticity associated with multiple sclerosis. (abst - 2011))
- Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration. (abst – 2011)
- Memory-rescuing effects of cannabidiol in an animal model of cognitive impairment relevant to neurodegenerative disorders. (abst – 2011)
- The interplay of cannabinoid and NMDA glutamate receptor systems in humans: preliminary evidence of interactive effects of cannabidiol and ketamine in healthy human subjects. (abst – 2011)
- Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent. (abst – 2011)
- Heterogeneity in the composition of marijuana seized in California. (abst – 2011)
- Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes. (abst – 2011)
- Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.(abst – 2011)
- A synthetic cannabinoid, CP55940, inhibits lipopolysaccharide-induced cytokine mRNA expression in a cannabinoid receptor-independent mechanism in rat cerebellar granule cells. (abst – 2011)
- Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action (abst – 2011)
- Cannabidiol (CBD as an Anti-Arrhythmic (abst – 2011))
- Cannabis could help treat epilepsy #1 (news – 2011)
- Cannabis could be used to treat epilepsy #2 (news – 2011)
- Marijuana Extract Might Help Prevent Chemotherapy-Related Nerve Pain (news – 2011)
- Marijuana component could ease pain from chemotherapy drugs (news – 2011)
- Another Study Confirms Anti-Cancer Effects of THC and CBD (news – 2011)
- Cannabinoid 'Completely' Prevents Chemotherapy-Induced Neuropathy, Study Says (news – 2011)
- Cannabidiol May Fight Alzheimer's Disease (news - 2011)
- Marijuana Compound Induces Cell Death In Hard-To-Treat Brain Cancer(news – 2011)
- Marijuana component may ease pain from chemo therapy drugs (news – 2011)
- Pot Compound Exerts Anticonvulsant Effects In Animal Models Of Epilepsy (news - 2011)
- New research provides hope for those with epilepsy (news - 2011)
- Cannabis Compound Induces Death Of Cells Associated With Liver Fibrosis (news – 2011)
- CBD Tops The Chart (news - 2011)
- Cannabidiol may help prevent paclitaxel-induced peripheral neuropathy (news – 2011)
- Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug. (full – 2012)
- Topical and Systemic Cannabidiol Improves Trinitrobenzene Sulfonic Acid Colitis in Mice. (full - 2012)
- Towards the use of non-psychoactive cannabinoids for prostate cancer. (full – 2012)
- Cannabidiol protects oligodendrocyte progenitor cells from inflammation-induced apoptosis by attenuating endoplasmic reticulum stress. (full – 2012)
- Medical use of cannabis. Cannabidiol: A new light for schizophrenia? (full - 2012)
- Cannabidiol inhibits growth and induces programmed cell death in kaposi sarcomaassociated herpesvirus-infected endothelium. (full – 2012)
- Endocannabinoids in nervous system health and disease: the big picture in a nutshell (full – 2012)
- Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. (full – 2012)
- Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report. (full – 2012)
- The Therapeutic Potential of Cannabis and Cannabinoids (full – 2012)
- Pharmacological interventions in the treatment of the acute effects of cannabis: a systematic review of literature (full – 2012)
- Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment. (full – 2012)
- Islet protection and amelioration of diabetes type 2 in Psammomys obesus by treatment with cannabidiol (link to PDF - 2012)
- Id-1 is a Key Transcriptional Regulator of Glioblastoma Aggressiveness and a Novel Therapeutic Target. (abst – 2012)
- Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. (abst – 2012)
- Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. (abst – 2012)
- Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a ` murine model of acute lung injury: Role for the adenosine A(2A receptor. (abst – 2012))
- Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects. (abst – 2012)
- The therapeutic potential of the endocannabinoid system for Alzheimer's disease. (abst – 2012)
- On Disruption of Fear Memory by Reconsolidation Blockade: Evidence from Cannabidiol Treatment. (abst – 2012)
- Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. (abst – 2012)
- Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid? (abst – 2012)
- Cannabidiol inhibits angiogenesis by multiple mechanisms. (abst – 2012)
- Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. (abst – 2012)
- Poly-ε-caprolactone microspheres as a drug delivery system for cannabinoid administration: Development, characterization and in vitro evaluation of their antitumoral efficacy. (abst – 2012)
- Effects of cannabinoids Δ(9-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP(+) affected murine mesencephalic cultures. (abst – 2012))
- Antipsychotic Profile of Cannabidiol and Rimonabant in an Animal Model of Emotional Context Processing in Schizophrenia. (abst – 2012)
- Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. (abst – 2012)
- Cannabidiol-induced apoptosis in murine microglial cells through lipid raft (abst – 2012)
- A critical review of the antipsychotic effects of Cannabidiol: 30 years of a translational investigation. (abst – 2012)
- Acute effects of a single, oral dose of d9-tetrahydrocannabinol (THC and cannabidiol (CBD) administration in healthy volunteers. (abst – 2012))
- Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures. (abst – 2012)
- The potential use of cannabidiol in the therapy of metabolic syndrome (abst – 2012)
- Cannabinoid-like anti-inflammatory compounds from flax fiber. (abst – 2012)
- Cannabidiol in Inflammatory Bowel Diseases: A Brief Overview. (abst – 2012)
- Cannabidiol treatment ameliorates ischemia/reperfusion renal injury in rats. (abst – 2012)
- Cannabidiol inhibits the reward-facilitating effect of morphine: involvement of 5-HT(1A receptors in the dorsal raphe nucleus. (abst – 2012))
- Phytocannabinoids as novel therapeutic agents in CNS disorders (abst – 2012)
- Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: Possible involvement of 5HT1A receptors. (abst – 2012)
- Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats. (abst – 2012)
- Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test. (abst – 2012)
- Magnitude of stimulation dictates the cannabinoid-mediated differential T cell response to HIVgp120. (abst – 2012)
- Endocannabinoid system and mood disorders: Priming a target for new therapies. (abst – 2012)
- Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. (abst – 2012)
- A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis. (abst – 2012)
- What place for cannabis extract in MS? (abst – 2012)
- Cannabidiol (CBD enhances lipopolysaccharide (LPS)-induced pulmonary inflammation in C57BL/6 mice. (abst – 2012))
- Cannabidiol for the treatment of cannabis withdrawal syndrome: a case report (abst – 2012)
- Cannabidiol and clozapine reverse MK-801-induced deficits in social interaction and hyperactivity in Sprague-Dawley rats. (abst – 2012)
- MicroRNAs and their role in the generation of myeloid derived suppressor cells (MDSC by cannabidiol in vivo (abst – 2012))
- Cannabidiol reduces host immune response and prevents cognitive impairments in Wistarrats submitted to pneumococcal meningitis (abst – 2012)
- Marijuana Compound May Beat Antipsychotics at Treating Schizophrenia (news – 2012)
- Getting the Flax Straight about Cannabidiol (news – 2012)
- Medical Marijuana: A "Cure" for Autism? (news – 2012)
- How marijuana could help cure obesity-related diseases (news – 2012)
- Cannabis can help treat obesity (news – 2012)
- Study: Cannabis Use Associated With Decreased Prevailence Of Diabetes (news – 2012)
- Researchers study neuroprotective properties in cannabis (news - 2012)
- How Medical Marijuana Is Giving a Six-Year-Old Boy New Life (news – 2012)
- Marijuana compound could stop aggressive cancer metastasis (news - 2012)
- Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers (news – 2012)
- Can marijuana stop cancer? (news – 2012)
- Cannabis For Infant's Brain Tumor, Doctor Calls Child "A Miracle Baby" (news – 2012)
- Buy It Now, It’s Legal – Medical Marijuana Cannabidiol (CBD from Industrial Hemp (news - 2012))
- Israel pushing ahead in medical marijuana industry (news – 2012)
- Marijuana Compound Treats Schizophrenia with Few Side Effects: Clinical Trial (news – 2012/a>)
- 5 Marijuana Compounds That Could Help Combat Cancer, Alzheimers, Parkinsons (If Only They Were Legal (news – 2012))
- Is Marijuana the Cancer Cure We’ve Waited For? (news – 2012)
- The Amazing Health Benefits of Juicing Raw Cannabis Leaves (news – 2012)
- Weaker Hemp Derivatives Can’t Compare to Full-Spectrum Marijuana Pills(news/ad- 2012 )
- Simple Method: Isolating & Extracting INDIVIDUAL Cannabinoids... from BadKittySmiles (forum post – 2012)
- Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: proapoptotic effects and underlying mechanisms. (full – 2013)
- Local delivery of cannabinoid-loaded microparticles inhibits tumor growth in a murine xenograft model of glioblastoma multiforme. (full – 2013)
- Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. (full – 2013)
- Industrial hemp decreases intestinal motility stronger than indian hemp in mice. (full – 2013)
- Modulating the endocannabinoid system in human health and disease: successes and failures (full – 2013)
- Natural Cannabinoids Improve Dopamine Neurotransmission and Tau and Amyloid Pathology in a Mouse Model of Tauopathy. (full – 2013)
- A Phase I, open-label, randomized, crossover study in three parallel groups to evaluate the effect of Rifampicin, Ketoconazole, and Omeprazole on the pharmacokinetics of THC/CBD oromucosal spray in healthy volunteers (full – 2013)
- Cannabidiol enhances consolidation of explicit fear extinction in humans. (abst – 2013)
- The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system. (abst – 2013)
- Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats. (abst – 2013)
- COX-2 and PPAR-γ Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells. (abst – 2013)
- Cannabidiol as potential anticancer drug (abst – 2013)
- Is the cardiovascular system a therapeutic target for cannabidiol? (abst – 2013)
- Endocannabinoid system modulator use in everyday clinical practice in the UK and Spain. (abst – 2013)
- A new multiple sclerosis spasticity treatment option: effect in everyday clinical practice and cost-effectiveness in Germany. (abst – 2013)
- The effects of cannabidiol on the antigen-induced contraction of airways smooth muscle in the guinea-pig. (abst – 2013)
- Impact of enzymatic and alkaline hydrolysis on CBD concentration in urine. (abst – 2013)
- Cannabidiol attenuates deficits of visuo-spatial associative memory induced by Δ9 tetrahydrocannabinol. (abst – 2013)
- Mechanisms Of Cannabidiol Neuroprotection In Hypoxic-Ischemic Newborn Pigs: Role Of 5HT1A And CB2 Receptors. (abst – 2013)
- The role of potassium BK channels in anticonvulsant effect of cannabidiol in pentylenetetrazole and maximal electroshock models of seizure in mice. (abst – 2013)
- Infusion of cannabidiol into infralimbic cortex facilitates fear extinction via CB1 receptors. (abst – 2013)
- Cannabidiol reduces cigarette consumption in tobacco smokers: Preliminary findings. (abst – 2013)
- Cannabidiol attenuates the long lasting cognitive deficits and anxiogenic-like behaviors promoted by murine cerebral malaria (abst – 2013)
- Interrogating Therapeutic Manipulation of the Endocannabinoid System in Human Colon (abst – 2013)
- Cardioprotective effect of cannabidiol in rats exposed to doxorubicin toxicity. (abst – 2013)
- Magnitude of stimulation dictates the cannabinoid-mediated differential T cell response to HIVgp120 (abst – 2013)
- Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptors activation in mice. (abst – 2013)
- Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors. (abst – 2013)
- CHANGES ON METABOLIC PARAMETERS INDUCED BY ACUTE CANNABINOID ADMINISTRATION (CBD, THC IN A RAT EXPERIMENTAL MODEL OF NUTRITIONAL VITAMIN A DEFICIENCY. (abst – 2013))
- Epigenetic Control of Skin Differentiation Genes by Phytocannabinoids (abst – 2013)
- Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype. (abst – 2013)
- Marijuana Verses Leading Pharmaceuticals In The Treatment of Colon Cancer (news – 2013)
- High on Health: Cannabinoids in the Food Supply (news – 2013)
- Fighting Cancer: Another Study Reveals the Cannabis and Cancer Link (news – 2013)
- Parents of epileptic N.J. tot lament medical marijuana delays (news – 2013)
- Charlotte’s Web Of Suffering: Six-Year-Old Colorado Girl With Dravet Syndrome Finds Relief From Marijuana High In CBD (news – 2013)
- Toronto family hopes for access to controversial treatment to cure baby’s rare epilepsy (news – 2013)
- Cannabis may help reverse dementia: study (news – 2013)
- FDA APPROVES CBD TREATMENT FOR CHILDREN (news – 2013)
*CBDA/ CANNABIDIOLIC ACID - precursor to Cannabidiol**- Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa (abst – 2007)
- Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis. (full – 2008)
- Phytocannabinoids for use in the treatment of cancer - Patent GB2478595 (A ―2011-09-14 (full – 2011))
- Cannabis as a Unique Functional Food (full – 2011)
- The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst – 2011)
- Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst – 2011)
- Cannabidiol May Fight Alzheimer's Disease (news – 2011)
- Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro. (abst – 2012)
- Heat Exposure of Cannabis sativa Extracts Affects the Pharmacokinetic and Metabolic Profile in Healthy Male Subjects. (abst – 2012)
- Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDAMB-231 breast cancer cell migration. (abst – 2012)
- Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. (abst – 2012)
- Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT(1A receptor activation. (abst – 2012))
- Effect of low doses of cannabidiolic acid and ondansetron on LiCl-induced conditioned gaping (a model of nausea-induced behaviour in rats. (abst – 2013))
CBDV/ CANNABIDIVARIN - phytocannabinoid- A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae (full - 2004))
- Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. (abst – 2005)
- Cannabidivarin is anticonvulsant in mouse and rat in vitro and in seizure models. (full – 2012)
- Cannabidivarin is anticonvulsant in mouse and rat. (full – 2012)
- Use of the phytocannabinoid cannabidivarin (cbdv in the treatment of epilepsy - Patent Applicaton #: #20120004251 (full – 2012))
- Phytocannabinoids as novel therapeutic agents in CNS disorders. (abst – 2012)
- Science/UK: Antiepileptic efficacy of cannabidivarin will be tested in clinical studies (news – 2012)
- Epigenetic Control of Skin Differentiation Genes by Phytocannabinoids (abst – 2013)
- Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV and Δ9 - tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism symptoms of nausea in rats. (abst – 2013))
- Cannabis Anti-Convulsant Shakes up Epilepsy Treatment (news – 2013)
- New cannabis discovery could lead to better treatments for epilepsy (news – 2013)
- New Study: Cannabinoids Protect the Brain and Heart From Injury (news – 2013)
*CBG/ CANNABIGEROL - phytocannabinoid, CB2 agonist** The precursor to the other cannabinoids. Geranyl pyrophosphate and olivetolic acid combine to form Cannabigerolic Acid (CBGA), which converts to Cannabigerol (CBG) through decarboxylation. It isn't found in high amounts in plants as it's often converted quickly to other cannabinoids. CBG has numerous health benefits, all that are enhanced synergistically by the consumption of other cannabinoids. CBG has very strong anti-inflammatory properties. It inhibits GABA (a neurotransmitter in your brain) uptake, which causes muscle relaxation and anti-anxiety effects. It also seems to have anti-depressive and anti-fungal properties.Enzymes help catalyze the CBG molecule form the other cannabinoids such as THCA, CBDA, CBC, etc by folding onto the molecule onto itself. - Phytocannabinoids (news – undated)
- Cannabinoids in clinical practice. (abst - 2000)
- Antibacterial cannabinoids from Cannabis sativa: a structure-activity study. (full - 2008)
- Patent application)
- Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. (full - 2010)
- Antidepressant-like effect of Delta(9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. (full - 2010))
- Detection of cannabigerol and its presumptive metabolite in human urine after Cannabis consumption. (abst - 2010)
- Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa (full – 2011)
- Phytocannabinoids for use in the treatment of cancer - Patent GB2478595 (A ― 2011-09-14 (full – 2011))
- Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews. (abst – 2011))
- Plasma and brain pharmacokinetic profile of cannabidiol (CBD, cannabidivarine (CBDV), Δ(9)-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessivecompulsive behaviour. (abst – 2011))
- Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. (abst – 2011)
- Phytocannabinoids as novel therapeutic agents in CNS disorders (abst – 2012)
- A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis. (abst – 2012)
- Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. (abst – 2012)
- 5 Marijuana Compounds That Could Help Combat Cancer, Alzheimers, Parkinsons (If Only They Were Legal (news – 2012))
- Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. (abst – 2013)
- The effect of CBG (BDS botanical cannabinoid extract on MCF-7 human breast carcinoma cells (abst – 2013))
- Epigenetic Control of Skin Differentiation Genes by Phytocannabinoids (abst – 2013)
CBN/ CANNABINOL - phytocannabinoid Cannabinol (CBN) is the product of THC degrading over time. Old or decarboxylated cannabis will have higher levels of CBN. It has a weak reaction to the CB1 and CB2 receptors, which leads to a sedative effect that makes you drowsy.CBN is currently being looked into for the treatment of bone disorders such as osteoporosis. Also appears to inhibit skin cell formation, which may lead to possible treatment for psoriasis. At around 140 degrees Celsius or 284 degrees Farenheight, THC starts to convert to CBN. - Pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol. (abst – 2005)
- Characterization of major phytocannabinoids, cannabidiol and cannabinol, as isoformselective and potent inhibitors of human CYP1 enzymes. (abst – 2010)
- Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. (abst – 2012)
- Analysis of cannabinoids in laser-microdissected trichomes of medicinal Cannabis sativa using LCMS and cryogenic NMR. (abst – 2012)
- 5 Marijuana Compounds That Could Help Combat Cancer, Alzheimers, Parkinsons (If Only They Were Legal (news – 2012))
- Hair analysis for THCA-A, THC and CBN after passive in vivo exposure to marijuana smoke. (abst – 2013)
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