Science Weeducation

Science Studying Cannabinoids

I know how difficult it can be to support your argument for the legalization of cannabis or medical marijuana. It's easy to say that cannabis cures cancer, but where is the evidence behind it? My goal with this article is to provide as much reference material possible for any arguments or essays that you may be concocting about cannabis - or simply for educational purposes. Click the following links to find the appropriate cannabinoids: CBC - CBD - CBDA - CBV - CBG - CBN

By far the most important thing I've learned is that THC and CBD can kill cancer cells
By far the most important thing I've learned is that THC and CBD can kill cancer cells

CBC / CANNABICHROMENE- Cannabis (hemp positive skin tests and respiratory symptoms (abst - 2000))

CBD/ CANNABIDIOLAntagonist of CB1 and CB2, GPR – 55 and 18 receptors Cannabidiol (CBD) is the second most common compound found in the cannabis plant. It produces a sedative high in contrast to the psychedelic high from THC, making you sleepy at higher doses. It also mitigates the effects of THC (particularly high dose, anxiety filled highs), not by reducing the amount of THC in the bloodstream, but by working it's sedative effects synergistically. The health benefits to CBD seem endless. CBD has been shown to have anti-inflammatory properties, even preventing the body from producing the chemical that causes inflammation. CBD has also been shown to reduce epileptic episodes, resulting in less seizures. CBD has even been found to bind to receptors in cancer cells and induce death. CBD exerts a protective property to damaged neurons, inhibiting the process in which nerves are damaged. Great for injury, protects brain from damage. CBD also fights MRSA, which is resistant to a number of antibiotics. Cannbidiol (CBD) is produced if there is enough CBDA synthase to catalyze Cannabigerolic Acid (CBGA) molecules into rings of Cannabidiolic Acid (CBDA). The CBDA is then converted to CBD through decarboxylation, either through heat or over time. - Phytocannabinoids (news – undated)

*CBDA/ CANNABIDIOLIC ACID - precursor to Cannabidiol**- Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa (abst – 2007)

CBDV/ CANNABIDIVARIN - phytocannabinoid- A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae (full - 2004))

*CBG/ CANNABIGEROL - phytocannabinoid, CB2 agonist** The precursor to the other cannabinoids. Geranyl pyrophosphate and olivetolic acid combine to form Cannabigerolic Acid (CBGA), which converts to Cannabigerol (CBG) through decarboxylation. It isn't found in high amounts in plants as it's often converted quickly to other cannabinoids. CBG has numerous health benefits, all that are enhanced synergistically by the consumption of other cannabinoids. CBG has very strong anti-inflammatory properties. It inhibits GABA (a neurotransmitter in your brain) uptake, which causes muscle relaxation and anti-anxiety effects. It also seems to have anti-depressive and anti-fungal properties.Enzymes help catalyze the CBG molecule form the other cannabinoids such as THCA, CBDA, CBC, etc by folding onto the molecule onto itself. - Phytocannabinoids (news – undated)

CBN/ CANNABINOL - phytocannabinoid Cannabinol (CBN) is the product of THC degrading over time. Old or decarboxylated cannabis will have higher levels of CBN. It has a weak reaction to the CB1 and CB2 receptors, which leads to a sedative effect that makes you drowsy.CBN is currently being looked into for the treatment of bone disorders such as osteoporosis. Also appears to inhibit skin cell formation, which may lead to possible treatment for psoriasis. At around 140 degrees Celsius or 284 degrees Farenheight, THC starts to convert to CBN. - Pharmacokinetics and metabolism of the plant cannabinoids, delta9-tetrahydrocannabinol, cannabidiol and cannabinol. (abst – 2005)

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